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Test Code FQPPS Porphyrins, Feces

Additional Codes

Torrance Memorial Laboratories Test Code:  283907411

Reporting Name

Porphyrins, F

Useful For

Evaluation of patients who present with signs or symptoms suggestive of porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria, congenital erythropoietic porphyria, erythropoietic protoporphyria, or X-linked protoporphyria

Testing Algorithm

The following algorithms are available:

-Porphyria (Acute) Testing Algorithm

-Porphyria (Cutaneous) Testing Algorithm

Method Name

High-Performance Liquid Chromatography (HPLC)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Fecal


Necessary Information


1. Weight of the non-homogenized sample

2. Collection duration

3. Include a list of medications the patient is currently taking.

4. Indicate if patient was compliant with the patient preparation requirements.



Specimen Required


Patient Preparation:

1. For 3 days before, as well as during, specimen collection, patient must not eat red meat or take any aspirin-containing medications.

2. For 24 hours before, as well as during, specimen collection, patient must not use barium, laxatives, or enemas.

Supplies: Stool Containers - 24, 48, 72 Hour Kit (T291)

Container/Tube: Stool containers

Specimen Volume: Entire collection (48, 72, or 96 hours). 24-Hour collection is adequate if the collection volume is at least 100 g

Collection Instructions:

1. Collect all stool specimens within a 24, 48, 72, or 96-hour timeframe.

2. Do not add preservative.

3. Send entire collection.

Additional Information: Specimens smaller than 100 g may not provide accurate results.


Specimen Stability Information

Specimen Type Temperature Time
Fecal Frozen (preferred) 14 days
  Refrigerated  14 days

Reject Due To

Specimens in preservative Reject

Reference Values

Uroporphyrin I: <120 mcg/24 h

Uroporphyrin III: <50 mcg/24 h

Heptacarboxyl I: <40 mcg/24 h

Heptacarboxyl III: <40 mcg/24 hours

Isoheptacarboxyl: <30 mcg/24 h

Hexacarboxyl I: <10 mcg/24 h

Hexacarboxyl III: <10 mcg/24 h

Isohexacarboxyl: <10 mcg/24 h

Pentacarboxyl I: <20 mcg/24 hours

Pentacarboxyl III: <20 mcg/24 h

Isopentacarboxyl: <80 mcg/24 hours

Coproporphyrin I: <500 mcg/24 h

Coproporphyrin III: <400 mcg/24 h

Isocoproporphyrin: <200 mcg/24 h

Protoporphyrin: <1,500 mcg/24 h

CoproIII/CoproI ratio: <1.20

Day(s) Performed

Monday, Thursday

Report Available

3 to 6 days

CPT Code Information

84126

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FQPPS Porphyrins, F 94548-5

 

Result ID Test Result Name Result LOINC Value
W6 Total weight 30078-0
TM70 Collection Duration 13363-7
15517 Uroporphyrin I 26691-6
15518 Uroporphyrin III 33585-1
15519 Heptacarboxyl I 49900-4
15520 Heptacarboxyl III 49901-2
15521 Isoheptacarboxyl 94549-3
15522 Hexacarboxyl I 94550-1
15523 Hexacarboxyl III 94551-9
15524 Isohexacarboxyl 94552-7
15525 Pentacarboxyl I 33623-0
15526 Pentacarboxyl III 33624-8
15527 Isopentacarboxyl 94553-5
15528 Coproporphyrin I 23845-1
15529 Coproporphyrin III 23846-9
15530 Isocoproporphyrin 33625-5
15534 Protoporphyrin 2891-0
15545 CoproIII/CoproI ratio 33618-0
81652 Interpretation (FQPPS) 59462-2
35013 Reviewed By 18771-6

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.