Test Code FQPPS Porphyrins, Feces
Additional Codes
Torrance Memorial Laboratories Test Code: 283907411
Reporting Name
Porphyrins, FUseful For
Evaluation of patients who present with signs or symptoms suggestive of porphyria cutanea tarda, hereditary coproporphyria, variegate porphyria, congenital erythropoietic porphyria, erythropoietic protoporphyria, or X-linked protoporphyria
Method Name
High-Performance Liquid Chromatography (HPLC)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
FecalNecessary Information
1. Weight of the non-homogenized sample
2. Collection duration
3. Include a list of medications the patient is currently taking.
4. Indicate if patient was compliant with the patient preparation requirements.
Specimen Required
Patient Preparation:
1. For 3 days before, as well as during, specimen collection, patient must not eat red meat or take any aspirin-containing medications.
2. For 24 hours before, as well as during, specimen collection, patient must not use barium, laxatives, or enemas.
Supplies: Stool Containers - 24, 48, 72 Hour Kit (T291)
Container/Tube: Stool containers
Specimen Volume: Entire collection (48, 72, or 96 hours). 24-Hour collection is adequate if the collection volume is at least 100 g
Collection Instructions:
1. Collect all stool specimens within a 24, 48, 72, or 96-hour timeframe.
2. Do not add preservative.
3. Send entire collection.
Additional Information: Specimens smaller than 100 g may not provide accurate results.
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Fecal | Frozen (preferred) | 14 days |
| Refrigerated | 14 days |
Reject Due To
| Specimens in preservative | Reject |
Special Instructions
Reference Values
Uroporphyrin I: <120 mcg/24 h
Uroporphyrin III: <50 mcg/24 h
Heptacarboxyl I: <40 mcg/24 h
Heptacarboxyl III: <40 mcg/24 hours
Isoheptacarboxyl: <30 mcg/24 h
Hexacarboxyl I: <10 mcg/24 h
Hexacarboxyl III: <10 mcg/24 h
Isohexacarboxyl: <10 mcg/24 h
Pentacarboxyl I: <20 mcg/24 hours
Pentacarboxyl III: <20 mcg/24 h
Isopentacarboxyl: <80 mcg/24 hours
Coproporphyrin I: <500 mcg/24 h
Coproporphyrin III: <400 mcg/24 h
Isocoproporphyrin: <200 mcg/24 h
Protoporphyrin: <1,500 mcg/24 h
CoproIII/CoproI ratio: <1.20
Day(s) Performed
Monday, Thursday
Report Available
3 to 6 daysCPT Code Information
84126
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FQPPS | Porphyrins, F | 94548-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| W6 | Total weight | 30078-0 |
| TM70 | Collection Duration | 13363-7 |
| 15517 | Uroporphyrin I | 26691-6 |
| 15518 | Uroporphyrin III | 33585-1 |
| 15519 | Heptacarboxyl I | 49900-4 |
| 15520 | Heptacarboxyl III | 49901-2 |
| 15521 | Isoheptacarboxyl | 94549-3 |
| 15522 | Hexacarboxyl I | 94550-1 |
| 15523 | Hexacarboxyl III | 94551-9 |
| 15524 | Isohexacarboxyl | 94552-7 |
| 15525 | Pentacarboxyl I | 33623-0 |
| 15526 | Pentacarboxyl III | 33624-8 |
| 15527 | Isopentacarboxyl | 94553-5 |
| 15528 | Coproporphyrin I | 23845-1 |
| 15529 | Coproporphyrin III | 23846-9 |
| 15530 | Isocoproporphyrin | 33625-5 |
| 15534 | Protoporphyrin | 2891-0 |
| 15545 | CoproIII/CoproI ratio | 33618-0 |
| 81652 | Interpretation (FQPPS) | 59462-2 |
| 35013 | Reviewed By | 18771-6 |
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.Forms
If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.