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Test Code COU Cobalt, 24 Hour, Urine

Reporting Name

Cobalt, 24 Hr, U

Useful For

Detecting cobalt exposure

 

Monitoring metallic prosthetic implant wear

 

This test is not useful to assess vitamin B12 activity.

Method Name

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Ordering Guidance


High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.



Necessary Information


24-Hour volume (in milliliters) is required.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 0.5 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Refrigerate specimen within 4 hours of completion of 24-hour collection.

3. See Metals Analysis Specimen Collection and Transport for complete instructions.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

0-17 years: Not established

≥18 years: 0.2-3.5 mcg/24 hours

Day(s) Performed

Tuesday, Wednesday, Friday

Report Available

1 to 4 days

CPT Code Information

83018

LOINC Code Information

Test ID Test Order Name Order LOINC Value
COU Cobalt, 24 Hr, U 29916-4

 

Result ID Test Result Name Result LOINC Value
80083 Cobalt, 24 Hr, U 29916-4
TM75 Collection Duration 13362-9
VL64 Urine Volume 3167-4

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

OK

Refrigerate

Preferred

Frozen

OK

50% Acetic Acid

No

Boric Acid

No

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

No

Toluene

No