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HelpTest Code B6PRO Vitamin B6 Profile (Pyridoxal 5-Phosphate and Pyridoxic Acid), Plasma
Additional Codes
Torrance Memorial Laboratories Test Code: 199861413
Useful For
Determining vitamin B6 status, including in persons who present with progressive nerve compression disorders, such as carpal tunnel and tarsal tunnel syndromes
Determining the overall success of a vitamin B6 supplementation program
Diagnosis and evaluation of hypophosphatasia
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| PLP | Pyridoxal 5-Phosphate (PLP), P | Yes | Yes |
| B6PA | Pyridoxic Acid (PA), P | No | Yes |
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Vitamin B6 Profile (PLP and PA), PSpecimen Type
Plasma HeparinShipping Instructions
Ship specimen in amber vial to protect from light.
Specimen Required
Patient Preparation:
1. Patient should fast overnight (12-14 hours); infants-should have specimen collected before next feeding. Water can be taken as needed.
2. For 24 hours before specimen collection, patient must not take multivitamins or vitamin supplements.
Supplies: Amber Frosted Tube, 5 mL (T915)
Collection Container/Tube: Green top (sodium or lithium heparin) or plasma gel separator (PST)
Submission Container/Tube: Amber vial
Specimen Volume: 1 mL
Collection Instructions:
1. Centrifuge at 4° C within 2 hours of collection.
2. Aliquot all plasma into amber vial and freeze immediately.
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Heparin | Frozen | 29 days | LIGHT PROTECTED |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
PYRIDOXAL 5-PHOSPHATE
5-50 mcg/L
PYRIDOXIC ACID
3-30 mcg/L
Day(s) Performed
Monday through Thursday, Saturday, Sunday
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82542
84207
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| B6PRO | Vitamin B6 Profile (PLP and PA), P | 95266-3 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 61065 | Pyridoxic Acid (PA), P | 1688-1 |
| 4047 | Pyridoxal 5-Phosphate (PLP), P | 30552-4 |