Sign in →

Test Code 62872388 PSA Free and Total

Performing Laboratory

Torrance Memorial Laboratories

Specimen Requirements

Submit the following specimen:
 

Specimen Type: Serum

Container/Tube: Serum gel

Spin Instructions:  Allow to sit for 30 minutes prior to spinning.  Spin within 2 hours of collection.

 

Also acceptable:  Red top tube

Specimen Transport Temperature

Refrigerated

 

Storage Temp Stability:
Refrigerated:  24 hours

Methodology

Chemiluminescent Microparticle Immunoassay.

Effective 01/21/2025, results were generated using the Abbott Alinity Immunoassay system. See interpretive data for important information

Reference Range

Reference Range Interp Data:
Results were generated using the Abbott Alinity Immunoassay system.  Values obtained from different assay methods cannot be used interchangeably.  The results of this assay should not be used as absolute evidence of the presence or absence of malignant disease.  Results should be used in conjunction with other diagnostic procedures.  Effective Date 01/21/2025
 

Probability of prostate cancer for men with nonsuspicious Digital Rectal Exam by percentage of free Prostate-Specific Antigen (PSA) and patient age for patients with Total PSA levels between 4.0 and 10 ng/mL

 

% Free PSA   50 to 64 Years   65 to 75 Years
0.00 - 10.00   56%   55%
10.01-15.00   24%   35%
15.01-20.00   17%   23%
20.01-25.00   10%   20%
>25   5%   9%

Catalona WJ, Partin AW, Slawin KM, et al. Use of the Percentage of Free Prostate-Specific Antigen to Enhance Differentiation of Prostate Cancer From Benign Prostatic Disease: A Prospective Multicenter Clinical Trial. JAMA. 1998;279(19):1542–1547. doi:10.1001/jama.279.19.1542

 

 

Limitations:                                
* Digital Rectal Examination (DRE) may cause clinically significant changes in the free PSA and free/total PSA ration in some patients. Additionally, prostatic massage, ultrasonography, cystoscopy, and needle biopsy may cause clinically significant elevations. Serum for free PSA determinations should be drawn before performing prostatic manipulations. PSA levels may also be increased following ejaculation.                                
* Hormonal therapy may affect PSA expression; therefore, a low PSA level after any treatment that includes hormonal therapy may not adequately reflect the presence of residual or recurrent disease.                                
* The measurement of free PSA or the free/total PSA ratio is not an absolute test for malignancy. The PSA values should be used in conjunction with information available from the clinical evaluation and other diagnostic procedures: e.g. symptoms, clinical impressions, digital rectal examination, transrectal ultrasound, etc. A prostatic biopsy is required for the diagnosis of cancer.                                

 

Day(s) Test Set up/TAT

Performed:

Daily

Not available STAT

TAT:

Routine: < 4 hrs

Aliases

PSA F&T

CPT Code

84153

84154