Reference Range

ENA Screen IgG Interpretative Data

<0.7    = Negative
0.7-1.0 = Equivocal
>1.0    = Positive

SymphonyS - ENA screen is based on recombinant U1-RNP (RNP 70, A, C), SS-A/Ro (52 kDa, 60 kDa), SS-B/La, Jo-1, Scl-70, Centromere B proteins and a synthetic SmD3 peptide as antigen and is useful as an aid in the clinical diagnosis of patients with systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), Sjogrens syndrome, scleroderma and polymyositis/dermatomyositis, in conjunction with other laboratory and clinical findings.

DNA DS Ab IgG Interpretive Data

<10   = Negative
10-15 = Equivocal
>15   = Positive

dsDNA - Positivity for anti-double stranded DNA (anti-dsDNA) IgG antibody is a diagnostic criterion of systemic lupus erythematosus (SLE). dsDNA antibodies (1:10 or greater) are found in 50-60 percent of SLE, 20-30 percent in Sjogren syndrome, 20-25 percent in mixed connective tissue disease (MCTD), and less than 5 percent in progressive systemic sclerosis (PSS). High titers of antibody to native (double stranded) DNA are specific for SLE.

*Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current data.