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Test Code 4409504021 Estradiol Level, Immunoassay

Important Note

This assay is for reproductive assessment (eg, IVF, conception).                                   

For other clinical indications, order EEST / Estradiol, Serum (link below). The preferred measurement of low serum estradiol concentrations in children, males, and postmenopausal females is liquid chromatography-tandem mass spectrometry (LC-MS/MS), order EEST / Estradiol Serum (link below).

This test should not be used when monitoring estradiol concentrations in patients being treated with Fulvestrant due to possible cross-reactivity. In these patients, estradiol concentrations should be measured using mass spectrometry; order EEST / Estradiol, Serum (link below).

Link to test EEST:  Estradiol, Serum - Torrance Memorial Laboratories (testcatalog.org)

Performing Laboratory

Torrance Memorial Laboratories

Specimen Requirements

Submit the following specimen:
 

Specimen Type: Serum

Container/Tube: Serum gel

Additional Instructions:   Allow to sit for 30 minutes prior to spinning.  Spin within 2 hours of collection.

 

Specimen Transport Temperature

Refrigerated

Storage Temp Stability:
Refrigerated Temperature: 7 days
 

Methodology

Chemiluminescent Microparticle Immunoassay

Reference Range

Reference Range Interp Data:        
Estradiol concentrations vary widely        
The limit of quantitation for estradiol measured by immunoassay is 24 pg/mL. Mass Spectrometry is the preferred method for measurement of low serum estradiol concentrations in children, males, and postmenopausal females

 

Population n Estradiol Concentration Value
Median Central 95% Range
(pg/mL) (pg/mL)
Normal Menstruating Females:      
Follicular Phase 385 54 21 - 251
Mid-Cycle Phase 105 196 38 - 649
Luteal Phase 466 99 21 - 312
Postmenopausal Females not on HRT 50 <10 <10 - 28
Postmenopausal Females on HRT* 22 28 <10 - 144
Males 101 23 11 - 44

Day(s) Test Set up/TAT

Performed:

Daily

Not available STAT

TAT:

Routine: < 4 hrs

Aliases

None

CPT Code

82670